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Part of the hippocampal formation, the subiculum essentially separates the hippocampus proper from the entorhinal neocortex of the parahippocampal gyrus. Whereas the dentate and hippocampus are primitive, 3-layered archicortex, the subiculum is transition cortex with more than 3 layers and is thus distinctive from the hippocampus. Fibers from the subiculum are a major component of the fornix.

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