(Perhaps the most significant tract in neuroanatomy/neurology) These are axons of cells of the cerebral cortex that descend all the way to the spinal cord and synapse on spinal motoneurons. The lateral corticospinal tract (in the lateral funiculus) consists of cortical fibers that decussated (crossed from left to right & vice versa) in the lower medulla. The much smaller anterior corticospinal tract consists of a minority of these cortical axons that do not cross in the medulla and instead descend in the anterior funiculus of the spinal cord.
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